HYPERMELANOSIS (SKIN PATCHES)
Hypermelanosis are skin diseases characterized by increased skin pigmentation and are due to multiple causes (genetic, metabolic, hormonal, inflammatory, nutritional, chemical, physical…).
They appear as “skin patches” localized in specific skin areas or diffuse and may be due to both an increase in the number of melanocytes (cells that produce melanin) and an increase in melanin (dark pigment produced by melanocytes) with a normal number of melanocytes.
With regard to the localization of the pigment, Hypermelanosis is classified into:
A) A) Epidermal
- Lentigo
- Ephelids
- Seborrheic keratoses/li>
B) Dermoepidermal
- Melasma
- Post-inflammatory hyperpigmentation
C) Dermal
- Tattoos
- Post-sclerotherapy hyperpigmentation
There are skin spots in which the pigment is not only represented by melanin:
- in post-inflammatory hyperpigmentation we find hemoglobin accumulations
- in post-sclerotherapy hyperpigmentation hemosiderin accumulations
- in tattoos there is an accumulation of exogenous pigments (decorative tattoos) or different foreign bodies (such as asphalt in post-traumatic tattoos).
Causes of Hypermelanosis
Patches often appear or accentuate in the photo-exposed regions because UVB rays, in particular, stimulate melanogenesis (the synthesis of melanin); this is the reason why sun exposure accentuates the appearance of dark spots. Many drugs can cause skin hyperpigmentation, preceded or not by inflammatory manifestations such as erythema, edema, desquamation, blisters, vesicles…; among these drugs are salicylates (aspirin) or barbiturates.
There are photosensibilising substances, or substances that determine a particular reactivity of the skin when it is exposed to solar radiation (for example bergamot oil).
Melasma is a hypermelanosis that affects only the photo-exposed areas. It typically occurs on the face (cheeks, forehead, upper lip) with bilateral and symmetrical lesions and mainly affects women who are pregnant or receiving oral contraceptives.
THypermelanosis therapy
Epidermal hypermelanosis, or the most superficial patches, are those that respond best to topical chemical and physical therapies, while deeper pigmentations, dermal or dermoepidermal, are difficult to resolve.
Each patient, based on the type of specific problem, can be treated with a PERSONALISED PROTOCOL, an outpatient therapy that acts in synergy with the specific home therapy prescribed to the patient.
HYPERMELANOSIS (SKIN PATCHES)
Hypermelanosis are skin diseases characterized by increased skin pigmentation and are due to multiple causes (genetic, metabolic, hormonal, inflammatory, nutritional, chemical, physical…).
They appear as “skin patches” localized in specific skin areas or diffuse and may be due to both an increase in the number of melanocytes (cells that produce melanin) and an increase in melanin (dark pigment produced by melanocytes) with a normal number of melanocytes.
With regard to the localization of the pigment, Hypermelanosis is classified into:
A) A) Epidermal
- Lentigo
- Ephelids
- Seborrheic keratoses/li>
B) Dermoepidermal
- Melasma
- Post-inflammatory hyperpigmentation
C) Dermal
- Tattoos
- Post-sclerotherapy hyperpigmentation
There are skin spots in which the pigment is not only represented by melanin:
- in post-inflammatory hyperpigmentation we find hemoglobin accumulations
- in post-sclerotherapy hyperpigmentation hemosiderin accumulations
- in tattoos there is an accumulation of exogenous pigments (decorative tattoos) or different foreign bodies (such as asphalt in post-traumatic tattoos).
Causes of Hypermelanosis
Patches often appear or accentuate in the photo-exposed regions because UVB rays, in particular, stimulate melanogenesis (the synthesis of melanin); this is the reason why sun exposure accentuates the appearance of dark spots. Many drugs can cause skin hyperpigmentation, preceded or not by inflammatory manifestations such as erythema, edema, desquamation, blisters, vesicles…; among these drugs are salicylates (aspirin) or barbiturates.
There are photosensibilising substances, or substances that determine a particular reactivity of the skin when it is exposed to solar radiation (for example bergamot oil).
Melasma is a hypermelanosis that affects only the photo-exposed areas. It typically occurs on the face (cheeks, forehead, upper lip) with bilateral and symmetrical lesions and mainly affects women who are pregnant or receiving oral contraceptives.
THypermelanosis therapy
Epidermal hypermelanosis, or the most superficial patches, are those that respond best to topical chemical and physical therapies, while deeper pigmentations, dermal or dermoepidermal, are difficult to resolve.
Each patient, based on the type of specific problem, can be treated with a PERSONALISED PROTOCOL, an outpatient therapy that acts in synergy with the specific home therapy prescribed to the patient.